Published May 1979
| Version v1
Journal article
Renal hyperconcentration of /sup 99m/Tc-HEDP in experimental acute tubular necrosis
Description
The effect of transient renal ischemia on renal concentration and distribution of /sup 99m/Tc-HEDP, /sup 99m/Tc-DMSA, and /sup 99m/Tc-DTPA was compared in rabbits with acute tubular necrosis. Scintigrams were obtained after injection in normal rabbits or ones with unilateral or bilateral ischemia. /sup 99m/Tc-HEDP concentration in ischemic tissue was 8 to 18 times normal 1 to 4 hrs after injection, and the resulting images delineated the morphological changes in the ischemic kidneys more accurately than those obtained with DMSA or DTPA. Calcium concentration in the ischemic kidneys increased sixfold. /sup 99m/Tc-HEDP may be useful in evaluation of renal failure secondary to tubular injury
Additional details
Additional titles
- Augmented title (English)
- Comparison of renal distribution of /sup 99m/Tc-HEDP, -DMSA, and -DTPA in rabbits
Publishing Information
- Journal Title
- Radiology
- Journal Volume
- 131
- Journal Issue
- 2
- Series
- Radiology.
- Journal Page Range
- 491-495
- ISSN
- 0033-8419
Conference
- Title
- 25. annual meeting of the Society of Nuclear Medicine.
- Dates
- 27 Jun 1978.
- Place
- Anaheim, CA, USA.
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 10487707
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE; S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- BLOOD FLOW; CARBOXYLIC ACID ESTERS; COMPARATIVE EVALUATIONS; DIAGNOSIS; DISTRIBUTION; DTPA; DYNAMIC FUNCTION STUDIES; HDEHP; INTRAVENOUS INJECTION; ISCHEMIA; ISOMERIC NUCLEI; KIDNEYS; LABELLED COMPOUNDS; MEASURING METHODS; NECROSIS; RABBITS; RADIOPHARMACEUTICALS; SCINTISCANNING; TECHNETIUM 99; TISSUES; UROGENITAL SYSTEM DISEASES
- Descriptors DEC
- AMINO ACIDS; ANEMIAS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARBOXYLIC ACIDS; CARDIOVASCULAR DISEASES; CHELATING AGENTS; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DISEASES; DRUGS; ESTERS; HEMIC DISEASES; HOURS LIVING RADIOISOTOPES; INJECTION; INTAKE; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MEDICINE; NUCLEAR MEDICINE; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC PHOSPHORUS COMPOUNDS; ORGANS; PATHOLOGICAL CHANGES; PHOSPHORIC ACID ESTERS; RADIOACTIVE MATERIALS; RADIOISOTOPE SCANNING; RADIOISOTOPES; SYMPTOMS; TECHNETIUM ISOTOPES; VERTEBRATES; YEARS LIVING RADIOISOTOPES