Published January 1990 | Version v1
Journal article

Neutron therapy for locally advanced head and neck squamous cell carcinoma: Optimum dose search

  • 1. King Faisal Specialist Hospital and Research Centre, Riyadh (Saudi Arabia)

Description

28 patients with locally advanced primary squamous cell carcinoma of the head and neck received neutron therapy and were randomized between two dose levels: 145 cGy nγ x twelve fractions, three fractions per week (total 17.4 Gy nγ). 155 cGy nγ x twelve fractions, three fractions per week (total 18.6 Gy nγ). Acute toxicity for skin, mucous membrane, salivary and subcutaneous tissues was graded using the EORTC/RTOG scoring system. Analysis indicates 17.4 Gy nγ as 'safe'. A further twelve patients are to be assigned to the higher dose (18.6 Gy nγ) before making a final dose selection. (orig.)

Additional details

Publishing Information

Journal Title
Strahlentherapie und Onkologie
Journal Volume
166
Journal Issue
1
Series
Strahlenther. Onkol.
Journal Page Range
111-113
ISSN
0179-7158
CODEN
STONE

Conference

Title
International workshop on particle therapy.
Dates
28-29 Oct 1988.
Place
Essen (Germany, F.R.).

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
21031992
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Resource subtype / Literary indicator
Conference
Descriptors DEI
CARCINOMAS; CYCLOTRONS; EFFICIENCY; FRACTIONATED IRRADIATION; HEAD; NECK; NEUTRON BEAMS; PATIENTS; RADIOTHERAPY; SIDE EFFECTS
Descriptors DEC
ACCELERATORS; BEAMS; BODY; BODY AREAS; CYCLIC ACCELERATORS; DISEASES; IRRADIATION; MEDICINE; NEOPLASMS; NUCLEON BEAMS; PARTICLE BEAMS; THERAPY