Published 1985 | Version v1
Book Metadata-only

Effects of irradiation on the differentiation pathway of bone resorbing cells

Creators

  • 1. Rijksuniversiteit Leiden (Netherlands). Lab. voor celbiologie en histologie

Description

The present study was designed to obtain more insight in the osteoclast (OC) differentiation pathway and the radiation effects thereupon using histochemical detection of the osteoclastic acid phosphatase activity in embryonic long bones. The authors describe the identification of the periosteal mononuclear pre-OC's, displaying tartrate-resistant enzyme activity. Additionally, the effects of irradiation on the pre-OC kinetics in relation to the formation of multinucleated OC's in embryonic long bones in vitro was described. (Auth.)

Additional details

Additional titles

Subtitle (English)
Use of histochemical demonstration of tartrate-resistant acid phosphatase activity

Publishing Information

Publisher
Elsevier/Excerpta Medica.
Imprint Place
Amsterdam (Netherlands)
ISBN
0-444-80659-8
Imprint Title
Current advances in skeletogenesis: induction, biomineralization, bone seeking hormones, congenital and metabolic bone diseases
Imprint Pagination
498 p.
Journal Volume
643
Series
International congress series.
Journal Page Range
p. 51-57.

Conference

Title
6. International workshop on calcified tissues.
Dates
18-23 Mar 1984.
Place
Kiryat-Anavim (Israel).

INIS

Country of Publication
Netherlands
Country of Input or Organization
Netherlands
INIS RN
16060549
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ACID PHOSPHATASE; BIOLOGICAL RADIATION EFFECTS; BONE CELLS; CELL DIFFERENTIATION; EMBRYOS; X RADIATION
Descriptors DEC
ANIMAL CELLS; BIOLOGICAL EFFECTS; CONNECTIVE TISSUE CELLS; ELECTROMAGNETIC RADIATION; ENZYMES; ESTERASES; HYDROLASES; IONIZING RADIATIONS; ORGANIC COMPOUNDS; PHOSPHATASES; RADIATION EFFECTS; RADIATIONS; SOMATIC CELLS

Optional Information

Notes
14 refs.; 1 figure; 1 table.