Chemical characterization of complexation behavior of pertechnetate with cysteine
Creators
- 1. National Tsing Hua Univ. Hsinchu (China). Inst. of Nuclear Science
- 2. Institute of Nuclear Energy Research, Lung-Tan (China)
Description
The labeling behavior of cysteine with 99TcO4- ion and/or 99mTcO4- ion at different cysteine concentrations reductant and pH values has been studied by chromatography, and the labeling yield was calculated. Three major Tc-complexes, yellow, reddish brown and green can be separated by gel filtration chromatography (GFC). Thin layer chromatography (TLC), high performance liquid chromatography (HPLC) and ion-exchange chromatography (IC) were used to separate the complexes collected from GFC. The TLC, HPLC data show the pertechnetate accompanied with a yellow complex; the green and purple complex contain more than two complexes. Electrophoresis and IC data show that the complexes carry a negative charge. The conductivity, UV-VIS, flow beta-detector with HPLC and autoradiography are also applied to analyze complex formation. (author) 20 refs.; 13 figs.; 5 tabs
Additional details
Publishing Information
- Journal Title
- Journal of Radioanalytical and Nuclear Chemistry
- Journal Volume
- 159
- Journal Issue
- 1
- Journal Page Range
- p. 129-144.
- ISSN
- 0236-5731
- CODEN
- JRNCDM
INIS
- Country of Publication
- Hungary
- Country of Input or Organization
- Hungary
- INIS RN
- 24029076
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Resource subtype / Literary indicator
- Numerical Data
- Descriptors DEI
- ABSORPTION SPECTRA; CHEMICAL PREPARATION; CHROMATOGRAPHY; CYSTEINE; ELECTROPHORESIS; EXPERIMENTAL DATA; LABELLING; LEACHING; PERTECHNETATES; PH VALUE; RADIOPHARMACEUTICALS; TECHNETIUM COMPLEXES; TECHNETIUM 99; TIN CHLORIDES
- Descriptors DEC
- AMINO ACIDS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CARBOXYLIC ACIDS; CHLORIDES; CHLORINE COMPOUNDS; COMPLEXES; DATA; DISSOLUTION; DRUGS; HALIDES; HALOGEN COMPOUNDS; HOURS LIVING RADIOISOTOPES; INFORMATION; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MATERIALS; NUCLEI; NUMERICAL DATA; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC SULFUR COMPOUNDS; OXYGEN COMPOUNDS; RADIOACTIVE MATERIALS; RADIOISOTOPES; SEPARATION PROCESSES; SPECTRA; SYNTHESIS; TECHNETIUM COMPOUNDS; TECHNETIUM ISOTOPES; THIOLS; TIN COMPOUNDS; TIN HALIDES; TRANSITION ELEMENT COMPLEXES; TRANSITION ELEMENT COMPOUNDS; YEARS LIVING RADIOISOTOPES