Published March 7, 2000 | Version v1
Report Open

Accreditation to supervise researches

Creators

Description

After completing a thesis on neutralizing antibodies and serum facilitating factors in human immunodeficiency virus infections, the author studied: the effect of gamma irradiation on macrophage monocytes (ART 13, ART 15, PO14, AF 22); interactions between HIV-infected cells and the extracellular matrix (ART 20, PO15, PO 21, AF 14, AF 17, AF 18); maternal-fetal transmission of HIV; interactions between HIV and B lymphocytes (ART 9, ART 10, ART 17, ART 18, PO 7, PO10, AF 13, AF 16, AF 19, AF 20); expression of glutamate transporters by macrophages. He then details his research project on the pathophysiology of central nervous system damage in HIV infections: the roles of astrocytes and microglial cells. (author)

Abstract (French)

Apres avoir effectue une these sur les anticorps neutralisants et facteurs seriques facilitants dans les infections a virus de l'immunodeficience humaine (VIH), l'auteur a etudie: l'effet de l'irradiation gamma sur les monocytes macrophages (ART 13, ART 15, PO14, AF 22); les interactions entre les cellules infectees par le VIH et la matrice extracellulaire (ART 20, PO15, PO 21, AF 14, AF 17, AF 18); la transmission materno-foetale du VIH; les interactions entre le VIH et les lymphocytes B (ART 9, ART 10, ART 17, ART 18, PO 7, PO10, AF 13, AF 16, AF 19, AF 20); l'expression des transporteurs du glutamate par les macrophages. Il detaille ensuite son projet de recherche sur la physiopathologie de l'atteinte du systeme nerveux central dans les infections a VIH: les roles des astrocytes et des cellules microgliales

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Additional details

Additional titles

Original title (French)
Habilitation a Diriger les Recherches

Publishing Information

Imprint Pagination
181 p.
Report number
FRCEA-TH--16329

INIS

Country of Publication
France
Country of Input or Organization
France
INIS RN
54115639
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S60: APPLIED LIFE SCIENCES;
Resource subtype / Literary indicator
Thesis
Descriptors DEI
AIDS VIRUS; ANTIBODIES; CENTRAL NERVOUS SYSTEM; GAMMA RADIATION; IN VITRO; KINETICS; LYMPH NODES; LYMPHOCYTES; LYMPHOKINES; MACROPHAGES; MONOCYTES
Descriptors DEC
ANIMAL CELLS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CONNECTIVE TISSUE CELLS; ELECTROMAGNETIC RADIATION; GROWTH FACTORS; IONIZING RADIATIONS; LEUKOCYTES; LYMPHATIC SYSTEM; MATERIALS; MICROORGANISMS; MITOGENS; NERVOUS SYSTEM; ORGANIC COMPOUNDS; PARASITES; PHAGOCYTES; PROTEINS; RADIATIONS; SOMATIC CELLS; VIRUSES

Optional Information

Notes
265 refs.; Available from the INIS Liaison Officer for France, see the INIS website for current contact and E-mail addresses