Published May 1977
| Version v1
Journal article
Serum alkaline phosphatases as indicators of radiation damage in rats
Description
The effects of whole-body, single-dose irradiations (100, 300, 500, 800 R 60Co γ rays) on the activities of isoenzymes of alkaline phosphatase in the serum of rats have been studied. The degree of changes in the intestinal and liver isoenzyme activity was directly dependent on the radiation dose. A marked, time-dependent decrease in the bone isoenzyme activity in serum was found only after 800 R. A computer processing of biochemical data by stepwise discriminant analysis enabled an early diagnosis of postradiation injury of the gut and bone and to classify the irradiated rats according to the radiation dose
Additional details
Additional titles
- Augmented title (English)
- Gamma radiation
Identifiers
- DOI
- 10.2307/3574597;
Publishing Information
- Journal Title
- Radiation Research
- Journal Volume
- 70
- Journal Issue
- 2
- Series
- Radiat. Res.
- Journal Page Range
- 406
- ISSN
- 0033-7587
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 8337604
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- ALKALINE PHOSPHATASE; BIOLOGICAL INDICATORS; BIOLOGICAL RADIATION EFFECTS; BLOOD SERUM; BONE TISSUES; COMPUTERS; DOSE-RESPONSE RELATIONSHIPS; GAMMA RADIATION; INTESTINES; LIVER; METABOLISM; RADIATION INJURIES; RATS; TIME DEPENDENCE
- Descriptors DEC
- ANIMALS; BIOLOGICAL EFFECTS; BODY; CONNECTIVE TISSUE; DIGESTIVE SYSTEM; DISEASES; ELECTROMAGNETIC RADIATION; ENZYMES; ESTERASES; GASTROINTESTINAL TRACT; GLANDS; HYDROLASES; INJURIES; IONIZING RADIATIONS; MAMMALS; ORGANIC COMPOUNDS; ORGANS; PHOSPHATASES; RADIATION EFFECTS; RADIATIONS; RODENTS; TISSUES; VERTEBRATES
Optional Information
- Notes
- Updated automatically by Metadata and Full-Text Enrichment Agent