Published September 1989 | Version v1
Journal article

Radiation protection by Shigoka extract on split-dose irradiation in mice

  • 1. Osaka Prefectural Radiation Research Institute (Japan)

Description

Radioprotective effect of a Shigoka extract was studied on split-dose irradiation. Mice were exposed to 4 Gy x 4 or 3 Gy x 4 for examining survival ratio or hemogram, respectively. The extract was i.p. injected immediately after each irradiation. The extract significantly (p<0.001) increased the survival ratio, and it increased leukocyte count within the period of the death (days 2-12 after the final exposure). Cerebral hemorrhage after 4 Gy x 4 was diminished by the extract. Recovery of leukocytogenesis seems much more important for survival at split-dose irradiation than at single acute irradiation. (author)

Additional details

Publishing Information

Journal Title
Journal of Radiation Research
Journal Volume
30
Journal Issue
3
Series
J. Radiat. Res.
Journal Page Range
247-254
ISSN
0449-3060
CODEN
JRARA