Published July 1983 | Version v1
Journal article Metadata-only

RBE of spleen CFU-S to low dose rate Cf-252 or photon radiation in vivo

Creators

  • 1. Univ. of Kentucky Medical Center, Lexington

Description

The biological effects of low dose rate (LDR) Cf-252 radiation were compared to LDR Cs-137 photon radiation and acute 60Co radiation. The RBE/sub n/ for endogenous CFU-S in vivo was 2.1 for neutron radiation at a dose rate of 9.9 cGy/hr of Cf-252 radiation. The value was onsistent with previous in vitro experiments where a value of 2.1 was found. For the low doses and low dose rates studied, we tested an acute assay dose following the LDR irradiation to determine dose-effect and RBE/sub n/. Organ size shrinkage and regeneration patterns after LDR Cf-252 and Cs-137 were also studied and showed greater growth delay for Cf-252 irradiated lympho-hemopoietic tissues

Additional details

Publishing Information

Journal Title
Int. J. Radiat. Oncol., Biol. Phys.
Journal Volume
9
Journal Issue
7
Series
Int. J. Radiat. Oncol., Biol. Phys.
Journal Page Range
1049-1056
ISSN
0360-3016

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
15009179
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; CALIFORNIUM 252; CESIUM 137; CFU; COBALT 60; DOSE RATES; FISSION NEUTRONS; GAMMA RADIATION; IN VIVO; LOW DOSE IRRADIATION; MICE; RBE; SPLEEN
Descriptors DEC
ACTINIDE NUCLEI; ALPHA DECAY RADIOISOTOPES; ANIMALS; BARYONS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BODY; CALIFORNIUM ISOTOPES; CESIUM ISOTOPES; COBALT ISOTOPES; ELECTROMAGNETIC RADIATION; ELEMENTARY PARTICLES; EVEN-EVEN NUCLEI; FERMIONS; HADRONS; HEAVY NUCLEI; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IONIZING RADIATIONS; IRRADIATION; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MINUTES LIVING RADIOISOTOPES; NEUTRONS; NUCLEI; NUCLEONS; ODD-EVEN NUCLEI; ODD-ODD NUCLEI; ORGANS; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; RODENTS; VERTEBRATES; YEARS LIVING RADIOISOTOPES