Effect of Diamine in Amine-Functionalized MIL-101 for Knoevenagel Condensation

Have demonstrated that amines with different basicities successfully functionalized into the pores of MIL-101 and amine functionalized chromium terephthalate used as a base catalyst. The catalytic activity of amine functionalized MIL-101 in Knoevenagel condensation of ethylcyanoacetate and benzaldehyde depends on their basi-cities. The reactivity of these catalytic materials could be also affected by their pore size and/or surface area, which governs the facile diffusion of the molecules through the channels of the MIL-101. The present strategy ensures the development of new functionalities and lead to MOF applications of practically useful heterogeneous base catalysts for chemical transformations. Crystalline Metal-Organic Frameworks (MOFs) are currently an important kind of advanced functional materials due to their novel coordination structures, diverse topologies, and potential applications. As one of topical MOFs, porous chromium terephthalate with giant pores labeled MIL-101(Cr) possesses several unique features such as hierarchical pore structure including a mesoporous zeotype architecture, mesoporous cages and microporous windows, outstanding sorption properties, numerous unsaturated metal cation sites, and high hydrothermal and chemical stability. These properties have led to a number of application potential in catalysis, gas storage, drug delivery and adsorptive separation. One important challenge has to realize is funtionalization via incorporation of binding site or reactive centers for catalysis. The functionalization methods of metal organic frameworks (MOFs) in a wide range of applications are two possible approaches including pre- and post-modification with functional groups