Published 2005 | Version v1
Miscellaneous Metadata-only

A new method in the management of skin neoplasm using a flexible radioactive patch

Creators

  • 1. Korea Institute of Radiological and Medical Sciences, Seoul (Korea, Republic of)
  • 2. Yonsei University College of Medicine, Seoul (Korea, Republic of)
  • 3. Korea Cancer Center Hospital, Seoul (Korea, Republic of)
  • 4. Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

Description

We have developed a flexible radioactive polyurethane patch incorporating β-emitting radionuclide (166Ho) to treat malignant skin lesions. We covered the tumor surface (n=133) with the radioactive patch for 33.58 ± 5.33 minutes. Radiation dose delivered was 35 Gy for Bowen's disease (n=78), Kaposi sarcoma (n=25), actinic keratosis (n=5), and 50 Gy for BCC (n=17) and squamous carcinoma (n=8). Complete response was observed in 91.7% after the first therapeutic trial, 96.2% after 2nd and 97.7% after 4th trial with excellent cosmetic outcome for 31.15±13.88 months of follow-up. Radioactive patch therapy is effective for superficial skin cancers that are impractical for surgery

Part of:
Proceedings of international symposium on research reactor and neutron science

Additional details

Publishing Information

Publisher
KAERI
Imprint Place
Taejon (Korea, Republic of)
Imprint Title
Proceedings of international symposium on research reactor and neutron science
Imprint Pagination
922 p.
Journal Page Range
p. 103-105

Conference

Title
International symposium on research reactor and neutron science
Dates
11-13 Apr 2005
Place
Taejon (Korea, Republic of)

INIS

Country of Publication
Korea, Republic of
Country of Input or Organization
Korea, Republic of
INIS RN
37008046
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Resource subtype / Literary indicator
Conference, Non-conventional Literature
Descriptors DEI
HOLMIUM 166; NEOPLASMS; POLYURETHANES; SKIN; SURGERY
Descriptors DEC
BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; DAYS LIVING RADIOISOTOPES; DISEASES; HOLMIUM ISOTOPES; INTERMEDIATE MASS NUCLEI; ISOTOPES; MATERIALS; MEDICINE; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; ORGANIC POLYMERS; ORGANS; PETROCHEMICALS; PETROLEUM PRODUCTS; PLASTICS; POLYAMIDES; POLYMERS; RADIOISOTOPES; RARE EARTH NUCLEI; SYNTHETIC MATERIALS; YEARS LIVING RADIOISOTOPES

Optional Information

Notes
4 refs, 1 tab