Published May 2005 | Version v1
Journal article

Advances in magnetofection-magnetically guided nucleic acid delivery

  • 1. Institute of Experimental Oncology, Technical University, Ismaninger Str. 22, 81675 Munich (Germany)
  • 2. Department of Pediatrics, Ludwig-Maximilians-University, 80337 Munich (Germany)
  • 3. Institute of Physiology, Ludwig-Maximilians-University, 80336 Munich (Germany)
  • 4. Department of Veterinary Internal Medicine, Ludwig-Maximilians-University, 80539 Munich (Germany)
  • 5. Chemicell GmbH, 10823 Berlin (Germany)

Description

Magnetofection is nucleic acid delivery to cells supported and site-specifically guided by the attractive forces of magnetic fields acting on nucleic acid shuttles (vectors) which are associated with magnetic nanoparticles. Recent progress with the method confirms its general applicability with small and large nucleic acids and viruses. The method's therapeutic application as well as mechanistic studies will be discussed

Additional details

Identifiers

DOI
10.1016/j.jmmm.2005.01.032;
PII
S0304-8853(05)00121-6;

Publishing Information

Journal Title
Journal of Magnetism and Magnetic Materials
Journal Volume
293
Journal Issue
1
Journal Page Range
p. 501-508
ISSN
0304-8853
CODEN
JMMMDC

Conference

Title
5. International conference on scientific and clinical applications of magnetic carriers
Dates
20-22 May 2004
Place
Lyon (France)

INIS

Country of Publication
Netherlands
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
37029339
Subject category
S60: APPLIED LIFE SCIENCES;
Resource subtype / Literary indicator
Conference
Descriptors DEI
DELIVERY; DRUGS; GENE THERAPY; MAGNETIC FIELDS; MAGNETIC MATERIALS; NANOSTRUCTURES; NUCLEIC ACIDS; PARTICLES; THERAPEUTIC USES
Descriptors DEC
MATERIALS; MEDICINE; ORGANIC COMPOUNDS; THERAPY; USES

Optional Information

Copyright
Copyright (c) 2005 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.