Salvage surgery for recurrent laryngeal cancer following chemoradiotherapy
Creators
- 1. Hokkaido Univ., Graduate School of Medicine, Sapporo, Hokkaido (Japan)
Description
We analyzed salvage surgeries for recurrent laryngeal cancer following chemoradiotherapy. Between 1995 and 2001, all 23 patients with recurrent diseases after completion of chemoradiotherapy using carboplatin or cisplatin underwent total laryngectomy. Between 2002 and 2005, 10 patients underwent salvage surgeries after completion of chemoradiotherapy using docetaxel; total laryngectomy was performed in 6 patients and larynx-preserving surgeries were performed in 4 patients. Close follow-up for a longer period following chemoradiotherapy is recommended because not a few patients had recurrent diseases more than 2 years after completion of the treatment. Most patients who underwent total laryngectomy and insertion of indwelling voice prostheses achieved excellent to moderate speech ability. There was an increased risk of wound complications in patients undergoing salvage surgeries following chemoradiotherapy. Therefore, appropriate wound management for salvage surgeries is an important issue for head and neck surgeons. (author)
Additional details
Publishing Information
- Journal Title
- Jibi To Rinsho
- Journal Volume
- 54
- Journal Issue
- suppl.1
- Journal Page Range
- p. S61-S66
- ISSN
- 0447-7227
INIS
- Country of Publication
- Japan
- Country of Input or Organization
- Japan
- INIS RN
- 40027854
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- CARCINOMAS; CHEMOTHERAPY; COMBINED THERAPY; LARYNGECTOMY; LARYNX; LASERS; METASTASES; PATHOLOGICAL CHANGES; PATIENTS; RADIATION DOSES; RADIOTHERAPY; STANDARD OF LIVING
- Descriptors DEC
- DISEASES; DOSES; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; RADIOLOGY; RESPIRATORY SYSTEM; SURGERY; THERAPY