Published 2000
| Version v1
Miscellaneous
Effects of a prolonged irradiation with low dose-rate ionizing radiation on the hemopoiesis of mice
Creators
- 1. Inst. for Environmental Sciences, Rokkasho, Aomori (Japan)
Description
SPF C3H/HeN female mice were irradiated with 137Cs γ-rays at doses of 1-8 Gy at the dose rate of 20 mGy/22 h/day. After irradiation, the numbers of CFU-S and CFU-GM in the bone marrow were determined. Number of peripheral blood cells was also counted. The day 12-CFU-S, which is in the earliest stage of differentiation, decreased as the dose increased. Decreases in the numbers of day 7-CFU-S and CFU-GM were also observed. Regardless of the severe decrease in the number of hemopoietic stem cells, no remarkable changes were observed in the number of peripheral blood cells, indicating an enhanced differentiation of the precursor cells. (author)
Additional details
Publishing Information
- ISBN
- 4-9980604-2-2
- Imprint Title
- Proceedings of international symposium on biological effects of low dose radiation
- Imprint Pagination
- 256 p.
- Journal Page Range
- p. 122-128
Conference
- Title
- International symposium on biological effects of low dose radiation
- Dates
- 20-22 Oct 1999
- Place
- Rokkasho, Aomori (Japan)
INIS
- Country of Publication
- Japan
- Country of Input or Organization
- Japan
- INIS RN
- 31055132
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Conference, Non-conventional Literature
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; BONE MARROW CELLS; CESIUM 137; DOSE-RESPONSE RELATIONSHIPS; GAMMA RADIATION; LEUKOPOIESIS; LOW DOSE IRRADIATION; MICE; STEM CELLS
- Descriptors DEC
- ANIMAL CELLS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BLOOD FORMATION; CESIUM ISOTOPES; CONNECTIVE TISSUE CELLS; ELECTROMAGNETIC RADIATION; INTERMEDIATE MASS NUCLEI; IONIZING RADIATIONS; IRRADIATION; ISOTOPES; MAMMALS; NUCLEI; ODD-EVEN NUCLEI; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; RODENTS; SOMATIC CELLS; VERTEBRATES; YEARS LIVING RADIOISOTOPES