Published 1978 | Version v1
Miscellaneous Metadata-only

DNA repair contribution to mechanism of radioprotectors effects

Creators

Description

The role of DNA repair and its various aspects are considered in the action of radioprotectors, specifically: the effect of radioprotectors on the occurrence of primary disorders in DNA and on DNA degradation in irradiated cells; stimulation of repair processes after introduction of radioprotectors, blocking the intensification of primary disorders-DNA replications. Hypothetical molecular fundamentals of the biochemical mechanism in the action of radioprotectors are described. Experimental data are presented on one of the specific inhibitors of DNA replication synthesis-nalidixic acid. The prospects of using a complex of chemical radioprotectors, which contribute to DNA repair, are outlined

Additional details

Additional titles

Original title (Russian)
Вклад процессов репарации ДНК в механизм действия радиопротекторов

Publishing Information

Imprint Title
Information report. No. 21
Journal Page Range
p. 50-57.
Report number
INIS-mf--5636

Conference

Title
Plenum of the scientific council of the Academy of Sciences of the USSR on radiobiology problems devoted to the DNA reparation in mammal cells.
Dates
Mar 1977.
Place
Pushchino, USSR.

INIS

Country of Publication
USSR
Country of Input or Organization
USSR
INIS RN
12575334
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ANIMAL CELLS; BIOLOGICAL REPAIR; DNA; ENZYMES; GENETIC RADIATION EFFECTS; MAMMALS; MOLECULAR BIOLOGY; RADIOPROTECTIVE SUBSTANCES; RADIOSENSITIVITY; STRAND BREAKS
Descriptors DEC
ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BIOLOGICAL RECOVERY; DRUGS; GENETIC EFFECTS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; RADIATION EFFECTS; RESPONSE MODIFYING FACTORS; VERTEBRATES

Optional Information

Notes
Imprint:Informatsionnyj bulleten'. Vypusk 21.