Published March 2001
| Version v1
Journal article
Indirect genotoxic effect of gamma rays in human peripheral lymphocytes
Description
The aim of this study was to investigate the indirect genotoxic effect of various doses of gamma rays in human peripheral lymphocytes. For this aim, chromosome mediums were irradiated with various doses (2000, 4000, 8000, 16000 rad) of gamma rays. In this study, we were found that SCE (Sister Chromatid Exchange) was increased by gamma rays doses-dependently. In addition to these, percentages of abnormal cells with chromosomal abnormalities and CA (Chromosome Aberration)/Cell were increased by all doses of gamma rays compared to control. Besides, gamma rays decreased the MI dose-dependently. RI was not also reduced at all concentrations. (author)
Additional details
Publishing Information
- Journal Title
- Cytologia
- Journal Volume
- 66
- Journal Issue
- 1
- Journal Page Range
- p. 25-31
- ISSN
- 0011-4545
INIS
- Country of Publication
- Japan
- Country of Input or Organization
- Japan
- INIS RN
- 32025687
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- CHROMOSOMAL ABERRATIONS; DOSE-RESPONSE RELATIONSHIPS; GAMMA RADIATION; GENETIC RADIATION EFFECTS; HUMAN CHROMOSOMES; LYMPHOCYTES; RADICALS; SISTER CHROMATID EXCHANGES; TOXICITY
- Descriptors DEC
- ANIMAL CELLS; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BIOLOGICAL RADIATION EFFECTS; BLOOD; BLOOD CELLS; BODY FLUIDS; CHROMOSOMAL ABERRATIONS; CHROMOSOMES; CONNECTIVE TISSUE CELLS; ELECTROMAGNETIC RADIATION; GENETIC EFFECTS; IONIZING RADIATIONS; LEUKOCYTES; MATERIALS; MUTATIONS; RADIATION EFFECTS; RADIATIONS; SOMATIC CELLS