Published September 24, 2008
| Version v1
Journal article
Label-free detection of amyloid growth with microcantilever sensors
Creators
- 1. Nanoscience Centre, University of Cambridge, J J Thomson Avenue, Cambridge CB3 0FF (United Kingdom)
- 2. Institute of Integrated Systems, Department of Mechanical Engineering, School of Engineering and Physical Sciences, Heriot-Watt University, Edinburgh EH14 4AS (United Kingdom)
- 3. National Center of Competence for Research in Nanoscience, Institute of Physics, University of Basel, 4056 Basel (Switzerland)
- 4. Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW (United Kingdom)
Description
We present an approach for sensing protein aggregation using microcantilever systems. Results from both single cantilever experiments with internal reference and multicantilever array measurements with dedicated reference cantilevers are discussed. We show that in both cases protein aggregation on the sensor can be detected through associated changes in surface stress
Availability note (English)
Available from http://dx.doi.org/10.1088/0957-4484/19/38/384007Additional details
Identifiers
- DOI
- 10.1088/0957-4484/19/38/384007;
- PII
- S0957-4484(08)76167-1;
Publishing Information
- Journal Title
- Nanotechnology (Print)
- Journal Volume
- 19
- Journal Issue
- 38
- Journal Page Range
- [5 p.]
- ISSN
- 0957-4484
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 39112996
- Subject category
- S36: MATERIALS SCIENCE;
- Descriptors DEI
- AGGLOMERATION; DETECTION; NANOSTRUCTURES; PROTEINS; SENSORS; STRESSES
- Descriptors DEC
- ORGANIC COMPOUNDS