Prognostic factors in breast cancer

Even today the therapeutic strategy in the treatment of breast cancer is governed by prognostic factors, such as the size and type of the tumor, histological grading, and the number of lymph node metastases. In addition to other criteria, a decision must also be made as to whether changes in the radiotherapy technique (dosage, means of boostering) might lead to better results in the treatment of carcinoma of the breast in patients in poor condition. Several studies indicate that the effectiveness of irradiation can be improved (even with respect to longterm results) by alterations in the technique and careful adaptation to the surgical procedure. (orig.)