Clinical significance of measurement of changes of serum TNF-α and β2-m levels after radiation therapy in patients with nasopharyngeal cancer
Description
Objective: To study the clinical significance of changes of serum TNF-α and β2-m levels after radiation therapy in patients with nasopharyngeal cancer. Methods: Serum TNF-β and β2-m levels were measured with RIA in 31 patients with naso- pharyngeal cancer both before and after radiation therapy as well as in 35 controls. Results: Before radiation therapy the serum TNF - β2 and β2-m levels in patients were significantly higher than those in the controls (P<0.01), Three months after completion of radiation therapy, the serum TNF-α and β2-m levels dropped markedly and were not significantly different from those in controls (P > 0.05). Conclusion: Changes of serum TNF-β and β2-m contents after radiation therapy might be of prognostic value in patients with nasopharyngeal cancer. (authors)
Additional details
Publishing Information
- Journal Title
- Journal of Radioimmunology
- Journal Volume
- 19
- Journal Issue
- 4
- Journal Page Range
- p. 295-296
- ISSN
- 1008-9810
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 39096082
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BLOOD SERUM; CARCINOMAS; DIAGNOSIS; GLOBULINS-BETA; PATIENTS; PHARYNX; RADIOIMMUNOASSAY; RADIOTHERAPY; RESPONSE MODIFYING FACTORS
- Descriptors DEC
- BIOASSAY; BIOLOGICAL MATERIALS; BLOOD; BLOOD PLASMA; BODY; BODY FLUIDS; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; GLOBULINS; IMMUNOASSAY; ISOTOPE APPLICATIONS; MATERIALS; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; ORGANIC COMPOUNDS; ORGANS; PROTEINS; RADIOASSAY; RADIOIMMUNODETECTION; RADIOLOGY; RESPIRATORY SYSTEM; THERAPY; TRACER TECHNIQUES
Optional Information
- Notes
- 1 tab., 7 refs.