Published December 2004
| Version v1
Journal article
Reduction of carboxyhaemoglobin levels in the venous blood of cigarette smokers following the administration of carbogen
Creators
- 1. Department of Radiation Oncology, Vancouver Cancer Centre, BC Cancer Agency, Vancouver, BC (Canada)
- 2. UBC School of Medicine, University of British Columbia, Vancouver, BC (Canada)
- 3. Respiratory Therapy, Vancouver Cancer Center, BC Cancer Agency, Vancouver, BC (Canada)
- 4. Department of Radiation Oncology, Fraser Valley Cancer Center, BC Cancer Agency, Surrey, BC (Canada)
Description
Cigarette smokers have high carboxyhaemoglobin levels which can promote tumour radioresistance. Inhalation of carbogen gas shortens the half-life of carboxyhaemoglobin, increasing tumour radiosensitivity in animal models. Breathing 2.5% carbogen for 30 min results in a greater reduction in venous blood COHb levels than breathing 5% carbogen for 7 min
Additional details
Identifiers
- DOI
- 10.1016/j.radonc.2004.09.002;
- PII
- S0167-8140(04)00392-5;
Publishing Information
- Journal Title
- Radiotherapy and Oncology
- Journal Volume
- 73
- Journal Issue
- 3
- Journal Page Range
- p. 367-371
- ISSN
- 0167-8140
- CODEN
- RAONDT
INIS
- Country of Publication
- Ireland
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 36074470
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BLOOD; CARBOXYHEMOGLOBIN; HALF-LIFE; INHALATION; RADIOSENSITIVITY; RADIOTHERAPY; RESPIRATION
- Descriptors DEC
- BIOLOGICAL MATERIALS; BODY FLUIDS; INTAKE; MATERIALS; MEDICINE; NUCLEAR MEDICINE; RADIOLOGY; THERAPY
Optional Information
- Copyright
- Copyright (c) 2004 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.