Published July 1983
| Version v1
Journal article
Study of the structure and metabolism of nucleic acids in rat thymus during long-term administration of tritium oxide in different dosages
- 1. Institut Biofiziki, Moscow (USSR)
Description
During-3-month administration of tritium oxide (0.37, 0.925 and 1.85 MBq/g body weight) to rats one could observe the loss of the thymus weight, decrease in the concentration, content and production of DNA and RNA per organ, reduction of the molecular weight of single-stranded DNA, increase in the content of the salt-soluble polydeoxyribonucleotides, and activation of acidic DNAases. These changes were function of tritium dose daily administered to rats
Additional details
Additional titles
- Original title (Russian)
- Изучение структуры и обмена нуклеиновых кислот вилочковой железы крыс при длительном введении окиси трития в разных дозах
Publishing Information
- Journal Title
- Radiobiologiya
- Journal Volume
- 23
- Journal Issue
- 4
- Series
- Radiobiologiya.
- Journal Page Range
- 467-470
- ISSN
- 0033-8192
INIS
- Country of Publication
- Russian Federation
- Country of Input or Organization
- USSR
- INIS RN
- 15013354
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; BIOSYNTHESIS; CATALYSIS; CHRONIC INTAKE; DNA-ASE; DOSE-RESPONSE RELATIONSHIPS; METABOLISM; NUCLEIC ACIDS; RADIONUCLIDE KINETICS; RATS; THYMUS; TIME DEPENDENCE; TRITIUM OXIDES
- Descriptors DEC
- ANIMALS; BIOLOGICAL EFFECTS; BODY; ENZYMES; ESTERASES; HYDROGEN COMPOUNDS; HYDROLASES; INTAKE; KINETICS; LYMPHATIC SYSTEM; MAMMALS; ORGANIC COMPOUNDS; ORGANS; PHOSPHATASES; RADIATION EFFECTS; RODENTS; SYNTHESIS; TRITIUM COMPOUNDS; VERTEBRATES
Optional Information
- Notes
- For English translation see the journal Radiobiology (Translation) (USA).