Published July 1992 | Version v1
Journal article Metadata-only

Chromosome aberrations induced in human lymphocytes by U-235 fission neutrons. Pt. 2

Creators

  • 1. J. Stefan Inst., Ljubljana (Slovenia)

Description

Blood samples were spiked with Na-24 to study the separate effect of this nuclide on the incidence of chromosomal aberrations in neutron irradiated blood samples. A delay of 96 h was allowed before cultivation, so the results of chromosomal aberration analysis could be compared with the results obtained by direct irradiation of blood samples with U-235 fission neutrons. The absorbed dose was calculated using a simple conservative model. From the results obtained we can conclude that Na-24 alone was not the reason for the difference in the incidence of chromosomal aberrations between blood samples cultivated immediately after 'in vitro' irradiation by U-235 fission neutrons and samples which were cultivated after 96 h storage. (orig.)

Abstract (German)

Den Blutproben wurde Na-24 zugegeben, und dadurch wurde die separate Auswirkung dieses Radionuklides auf das Erscheinen von Chromosomenaberrationen in den mit Neutronen bestrahlten Blutproben beobachtet. Die Blutproben wurden mit 96stuendiger Zeitverschiebung kultiviert, wodurch der Vergleich mit den Resultaten, gewonnen bei direkter Bestrahlung der Blutproben mit U-235 Fissionsneutronen, ermoeglicht wurde. Die absorbierte Dosis wurde unter Anwendung des einfachen konservativen Modells errechnet. Aus den gewonnenen Resultaten laesst sich folgendes feststellen: Na-24 allein war kein Grund fuer den Unterschied beim Erscheinen der Chromosomenaberrationen zwischen den Blutproben, die sofort nach 'In-vitro'-Bestrahlung mit U-235 Fissionsneutronen kultiviert wurden, und denen, die mit 96stuendiger Zeitverschiebung kultiviert worden waren. (orig.)

Additional details

Additional titles

Subtitle (English)
Evaluation of the effect of the induced Na-24 activity on the chromosomal aberration yield

Publishing Information

Journal Title
Strahlentherapie und Onkologie
Journal Volume
168
Journal Issue
7
Journal Page Range
p. 406-411.
ISSN
0179-7158
CODEN
STONE4

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
24006006
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S61: RADIATION PROTECTION AND DOSIMETRY; S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; CHROMOSOMAL ABERRATIONS; EXTERNAL IRRADIATION; FISSION NEUTRONS; GENETIC RADIATION EFFECTS; IN VITRO; INTERNAL IRRADIATION; LYMPHOCYTES; MAN; RADIATION DOSES; RADIOACTIVATION; SODIUM 24; URANIUM 235
Descriptors DEC
ACTINIDE NUCLEI; ALPHA DECAY RADIOISOTOPES; ANIMAL CELLS; ANIMALS; BARYONS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; CONNECTIVE TISSUE CELLS; ELEMENTARY PARTICLES; EVEN-ODD NUCLEI; FERMIONS; GENETIC EFFECTS; HADRONS; HEAVY NUCLEI; HOURS LIVING RADIOISOTOPES; INTERNAL CONVERSION RADIOISOTO; IRRADIATION; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LEUKOCYTES; LIGHT NUCLEI; MAMMALS; MATERIALS; MILLISEC LIVING RADIOISOTOPES; MINUTES LIVING RADIOISOTOPES; MUTATIONS; NEUTRONS; NUCLEI; NUCLEONS; ODD-ODD NUCLEI; PRIMATES; RADIATION EFFECTS; RADIOISOTOPES; SODIUM ISOTOPES; SOMATIC CELLS; SPONTANEOUS FISSION RADIOISOTO; URANIUM ISOTOPES; VERTEBRATES; YEARS LIVING RADIOISOTOPES