99Tcm MIBI (Methoxy Isobutyl Isonitrile) - A new myocardial imaging agent for multiple functional studies: Discussion of technical parameters and comparison with thallium

99Tcm methoxy isobutyl isonitrile (MIBI) has been recently introduced to replace 201Tl chloride for myocardial imaging. It has been recommended for the following multiple functional studies: first-pass radionuclide angiocardiography, multigated and static myocardial imaging in multiple views, tomographic myocardial imaging and dual gated tomographic imaging. The paper reviews results in 24 patients studied with both 201Tl and 99Tcm MIBI within a maximum period of 2 weeks. All patients also had contrast coronary angiography and ventriculography within a maximum period of 4 weeks. The paper presents: (1) a comparison between the results of 201Tl and 99Tcm MIBI SPECT studies in these patients; (2) results of multiple functional studies done with 99Tcm MIBI and (3) technical parameters for 99Tcm MIBI studies that are of relative importance. (author). 14 refs, 2 tabs