Published July 1989
| Version v1
Journal article
Heat shock mRNA in mouse epidermis after UV irradiation
Creators
- 1. Laboratoires de Recherche Fondamentale de l'Oreal (France)
Description
Total RNA form murine epidermis was extracted at different times after irradiation with erythemogenic doses of ultraviolet light and hybridized to a DNA probe from the gene of a heat shock protein (hsp 70). An intense and transitory enrichment in RNA molecules hybridizeing to the DNA probe was found between 15 and 120 min after irradiation, followed by a return co control levels over the next 70 h. Dose-response analysis indicates that 30 min after the irradiation, the relative amount of RNA hybridizing to the hsp 70 DNA probe increases with the dose up to values greater than 5 times the control. (Author). 14 refs.; 5 figs
Additional details
Publishing Information
- Journal Title
- Mutation Research, DNAging: Genetic Instability and Aging
- Journal Volume
- 219
- Journal Issue
- 4
- Series
- Mutat. Res., DNAging: Genet. Instab. Aging.
- Journal Page Range
- 217-224
- ISSN
- 0921-8734
- CODEN
- MUREA
INIS
- Country of Publication
- Netherlands
- Country of Input or Organization
- Netherlands
- INIS RN
- 21039726
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- DNA; DOSE-RESPONSE RELATIONSHIPS; EPIDERMIS; GENETIC RADIATION EFFECTS; HYBRIDIZATION; MESSENGER-RNA; MICE; PROTEINS; ULTRAVIOLET RADIATION
- Descriptors DEC
- ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; ELECTROMAGNETIC RADIATION; EPITHELIUM; GENETIC EFFECTS; MAMMALS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; ORGANS; RADIATION EFFECTS; RADIATIONS; RNA; RODENTS; SKIN; TISSUES; VERTEBRATES