Published April 14, 2009
| Version v1
Journal article
Histotripsy of the Prostate for the Treatment of BPH: Chronic Results From a Canine Model
Creators
- 1. University of Michigan Department of Urology, Ann Arbor, MI (United States)
- 2. University of Michigan Department of Biomedical Engineering, Ann Arbor, MI (United States)
- 3. University of Michigan Department of Radiology, Ann Arbor, MI (United States)
Description
Histotripsy was evaluated as a non-invasive BPH treatment. The prostates of 21 canine subjects were targeted with one of three histotripsy doses. Prostates were harvested immediately, 7 days, or 28 days after treatment and assessed for changes. Lower treatment doses were found to produced scattered cellular disruption and hemorrhage that was sometimes reversible. Higher doses perforated the urethra and produced cavities in the glandular prostate that healed to leave an enlarged urinary channel.
Additional details
Identifiers
- DOI
- 10.1063/1.3131397;
Publishing Information
- Journal Title
- AIP Conference Proceedings
- Journal Volume
- 1113
- Journal Issue
- 1
- Journal Page Range
- p. 129-133
- ISSN
- 0094-243X
- CODEN
- APCPCS
Conference
- Title
- 8. international symposium on therapeutic ultrasound
- Dates
- 10-13 Sep 2008
- Place
- Minneapolis, MN (United States)
INIS
- Country of Publication
- United States
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 41039545
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE; S60: APPLIED LIFE SCIENCES;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- DOGS; DOSES; HEMORRHAGE; PROSTATE; RADIOTHERAPY; ULTRASONIC WAVES; URINARY TRACT; UROGENITAL SYSTEM DISEASES
- Descriptors DEC
- ANIMALS; BODY; DISEASES; GLANDS; MALE GENITALS; MAMMALS; MEDICINE; NUCLEAR MEDICINE; ORGANS; PATHOLOGICAL CHANGES; RADIOLOGY; SOUND WAVES; SYMPTOMS; THERAPY; VERTEBRATES
Optional Information
- Notes
- (c) 2009 American Institute of Physics