Published March 2018 | Version v1
Journal article Metadata-only

Ruthenium-catalyzed hydrogen isotope exchange of C(sp(3))-H bonds directed by a sulfur atom

Creators

  • 1. Univ Paris Saclay, CEA, SCBM, F-91191 Gif Sur Yvette, (France)
  • 2. UPS, CNRS, INSA, LPCNO,UMR 5215, 135 Ave Rangueil, F-31077 Toulouse, (France)
  • 3. CEA Saclay, DEN, DANS, DPC,SECR,LRMO, F-91191 Gif Sur Yvette, (France)
  • 4. Univ Paris Saclay, Univ Paris Sud, CNRS, ICMMO, RMN Milieu Oriente,UMR 8182, Bat 410, F-91405 Orsay, (France)

Description

We present here the first example of C(sp(3))-H activation directed by a sulfur atom. Based on this transformation catalyzed by Ru/C, we have developed a hydrogen isotope exchange reaction for the deuterium and tritium labelling of thioether substructures in complex molecules. (authors)

Availability note (English)

Available from doi: http://dx.doi.org/10.1039/c8cc00653a

Additional details

Identifiers

DOI
10.1039/c8cc00653a;

Publishing Information

Journal Title
ChemComm
Journal Volume
54
Journal Issue
no.24
Journal Page Range
p. 2986-2989
ISSN
1359-7345

INIS

Country of Publication
United Kingdom
Country of Input or Organization
France
INIS RN
52084391
Subject category
S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
Descriptors DEI
AMINES; CHEMISTRY; HEAVY WATER; HETEROGENEOUS CATALYSIS; ISOTOPIC EXCHANGE; NANOPARTICLES; RUTHENIUM; SULFONAMIDES
Descriptors DEC
AMIDES; ANTI-INFECTIVE AGENTS; ANTIMICROBIAL AGENTS; CATALYSIS; DEUTERIUM COMPOUNDS; DRUGS; ELEMENTS; HYDROGEN COMPOUNDS; METALS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANIC SULFUR COMPOUNDS; OXYGEN COMPOUNDS; PARTICLES; PLATINUM METALS; REFRACTORY METALS; TRANSITION ELEMENTS; WATER