BNCT filter optimisation using two- and three-dimensional discrete ordinates
Creators
- 1. Oak Ridge National Lab., TN (United States). Computational Physics and Engineering Div.
Description
An initial version of an optimisation code utilising two-dimensional radiation transport methods has been completed. This code is capable of predicting material compositions of a beam tube-filter geometry which can be used in a boron neutron capture therapy treatment facility to improve the ratio of the average radiation dose in a brain tumour to that in the healthy tissue surrounding the tumour. The optimisation algorithm employed by the code is very straightforward. After obtaining an estimate of the gradient of the dose ratio with respect to the nuclide densities in the beam tube-filter geometry, changes in the nuclide densities are made based on the magnitude and sign of the components of the dose ratio gradient, the magnitude of the nuclide densities, the upper and lower bound of each nuclide density, and the linear constraint that the sum of the nuclide density fractions in each material zone be less than or equal to 1.0. A local optimal solution is assumed to be found when the conditions are satisfied in every material zone. Three test cases which illustrate the optimisation procedure have been analysed and improvements in the dose ratio of 50% or more were obtained. (R.P.)
Additional details
Publishing Information
- Publisher
- OECD Publications
- Imprint Place
- Paris (France)
- ISBN
- 92-64-16020-5
- Imprint Title
- 3-D deterministic radiation transport computer programs. Features, applications and perspectives
- Imprint Pagination
- [430 p.]
- Journal Page Range
- p. 379-391
Conference
- Title
- 3-D deterministic radiation transport computer programs
- Dates
- 2-3 Dec 1996
- Place
- Paris (France)
INIS
- Country of Publication
- France
- Country of Input or Organization
- Nuclear Energy Agency of the OECD (NEA)
- INIS RN
- 29042537
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE; S99: GENERAL AND MISCELLANEOUS;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- ALGORITHMS; BORON; BRAIN; D CODES; DOSE-RESPONSE RELATIONSHIPS; FILTERS; GEOMETRY; NEUTRON CAPTURE THERAPY; OPTIMIZATION; RADIATION DOSES; RADIATION TRANSPORT; THREE-DIMENSIONAL CALCULATIONS
- Descriptors DEC
- BODY; CENTRAL NERVOUS SYSTEM; COMPUTER CODES; ELEMENTS; MATHEMATICS; MEDICINE; NERVOUS SYSTEM; NEUTRON THERAPY; ORGANS; RADIOTHERAPY; SEMIMETALS; THERAPY
Optional Information
- Notes
- 14 refs.