Published November 1984
| Version v1
Journal article
Single cell origin of radiation-induced thymic lymphoma in mice with cellular mosaicism
- 1. National Inst. of Radiological Sciences, Chiba (Japan)
Description
The clonal origin of radiation-induced thymic lymphoma was studied in mice with cellular mosaicism for phosphoglycerate kinase (PGK). Repeated whole-body X-irradiations (4 doses, 1.7 Gy each) with intervals of 7 days resulted in development of thymic lymphomas in the mosaic mice. PGK from all lymphomas gave only a single spot on electrophoresis. The results demonstrate the single cell origin of the thymic lymphoma. (author)
Additional details
Publishing Information
- Journal Title
- Jpn. J. Cancer Res.
- Journal Volume
- 75
- Journal Issue
- 11
- Series
- Jpn. J. Cancer Res.
- Journal Page Range
- 1002-1005
- ISSN
- 0016-450X
INIS
- Country of Publication
- Japan
- Country of Input or Organization
- Japan
- INIS RN
- 16063734
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL PATHWAYS; CLONE CELLS; LYMPHOMAS; MICE; MOSAICISM; MUTATION FREQUENCY; PATHOGENESIS; THYMUS; WHOLE-BODY IRRADIATION; X RADIATION
- Descriptors DEC
- ANIMALS; BODY; CELL CULTURES; DISEASES; ELECTROMAGNETIC RADIATION; EXTERNAL IRRADIATION; IONIZING RADIATIONS; IRRADIATION; LYMPHATIC SYSTEM; MAMMALS; NEOPLASMS; ORGANS; RADIATIONS; RODENTS; VERTEBRATES