Published June 2019 | Version v1
Journal article

Magnetic resonance imaging assessment of the substrate for hyposmia in patients with Parkinson's disease

  • 1. Department of Radiology, College of Medicine, The Catholic University of Korea, Seoul (Korea, Republic of)
  • 2. Department of Neurology, College of Medicine, The Catholic University of Korea, Seoul (Korea, Republic of)

Description

Highlights: • Gray matter structures of the normosmic and hyposmic PD were compared using MRI. • Aging effect was dominant in most of the subcortical gray matter changes. • Right thalamus of the hyposmic PD showed a decreased magnetic susceptibility. • Left thalamus of the hyposmic PD showed an increased magnetic susceptibility. • Disease-related structural changes in both thalami are associated with hyposmia in PD. -- Abstract: To assess whether multimodal magnetic resonance imaging (MRI) could detect neuroanatomical substrates that are distinctive to hyposmic Parkinson's disease (PD).

Additional details

Identifiers

DOI
10.1016/j.crad.2019.02.003;
PII
S0009926019300935;

Publishing Information

Journal Title
Clinical Radiology
Journal Volume
74
Journal Issue
6
Journal Page Range
p. 489.e9-489.e15
ISSN
0009-9260
CODEN
CLRAAG

INIS

Country of Publication
United Kingdom
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
55056875
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
AGING; MAGNETIC SUSCEPTIBILITY; NERVOUS SYSTEM DISEASES; NMR IMAGING; PATIENTS; SUBSTRATES; THALAMUS
Descriptors DEC
BODY; BRAIN; CENTRAL NERVOUS SYSTEM; DIAGNOSTIC TECHNIQUES; DISEASES; MAGNETIC PROPERTIES; NERVOUS SYSTEM; ORGANS; PHYSICAL PROPERTIES

Optional Information

Copyright
Copyright (c) 2019 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.