Solitary plasmacytomas of the rib: A rare tumor to keep in mind: Case report
Creators
- 1. Radiology Department, Mohammed V Military Teaching Hospital, Mohammed V University, Rue Taounat N 13, Bettana, Sale, Rabat (Morocco)
- 2. Anatomo-Pathology Department, Mohammed V Military Teaching Hospital, Mohammed V University, Rabat (Morocco)
Description
Around 5% of plasma cell neoplasias are solitary plasmacytomas, a tumor that is fairly rare. The presence of a localized tumor composed of monoclonal plasma cells that are the same as those found in multiple myeloma and the absence of symptoms that would suggest a disseminated form are used to establish the diagnosis. The thoracolumbar spine is the area most affected. Costal origin is infrequently described. In our case, the patient manifested a right anterosuperior chest wall mass. Imaging showed a mass of tissue with a significant zone of osteolysis of the first rib and no chest wall infiltration. Blood protein immuno electrophoresis disclosed a monoclonal kappa type IgG. Bence Jones proteinuria was positive, further suggesting a plasmacytomas of the rib. A percutaneous needle biopsy for pathology study and immunohistochemistry enabled the diagnosis of costal plasmacytomas. Search for other localizations was negative and the diagnosis of solitary plasmacytomas was retained. The patient received radiotherapy and has remained in remission for over a year. The pathology and imaging findings are used to make the diagnosis. Radiotherapy is the therapy of choice, but it presents a risk of progression to other bone lesions, medullary plasmacytosis, and multiple myeloma. There are no known factors that predict systemic recurrence. Surveillance is essential on a regular basis
Additional details
Publishing Information
- Journal Title
- Radiology Case Reports
- Journal Volume
- 18
- Journal Issue
- 1
- Journal Page Range
- p. 214-217
- ISSN
- 1930-0433
INIS
- Country of Publication
- United States
- Country of Input or Organization
- Egypt
- INIS RN
- 54068209
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- CHEMOTHERAPY; CHEST; COMPUTERIZED TOMOGRAPHY; ELECTROPHORESIS; IMMUNITY; NEOPLASMS; PLASMA CELLS; PROTEINS; RADIOTHERAPY
- Descriptors DEC
- ANIMAL CELLS; BODY; CONNECTIVE TISSUE CELLS; DIAGNOSTIC TECHNIQUES; DISEASES; MEDICINE; NUCLEAR MEDICINE; ORGANIC COMPOUNDS; RADIOLOGY; SOMATIC CELLS; THERAPY; TOMOGRAPHY