Primary intracranial chondrosarcoma: A report of 2 cases and literature review

Objective: To analyze the clinical data of 2 patients with primary intracranial chondrosarcoma, and to improve its climical awareness and management. Methods: One patient admitted to the hospital because of his left eye with oculomotor palsy, and he was considered as craniopharyngioma before operation and received radiotherapy after operation. The other patient admitted to the hospital for the vision loss, and he was considered as chordoma and received subtotal resection. Results: Both two patients were confirmed as chondrosarcoma by postoperative pathological examination. One patient's clinical symptoms relieved after operation, and there was no obvious progress from the begining of follow-up to now; the other patient died of severe intracranial infection on the 10th day after operation. Conclusion: Primary intracranial chondrosarcoma is easy to be misdiagnosed before operation and needs to be confirmed by postoperative pathology. Operation is the first choice for its treatment, and the postoperative radiotherapy can achieve the good results. (authors)