Published December 1975
| Version v1
Journal article
Regional blood flow in rats exposed to supralethal doses of whole body X-irradiation
Creators
- 1. Centre d'Etude de l'Energie Nucleaire, Mol (Belgium). Dept. de Radiobiologie
Description
Relative blood flow in different organs of the supralethally (3 kR) whole body X-irradiated rat was studied using labeled 15μ microspheres. Immediately after irradiation blood flow in brain diminishes. From 10 to 20 hrs a phase of increase in blood flowing to many parenchymal organs ensues. A second maximum occurs from 45 to 50 hrs and a third one at 60 hrs. In most organs except in brain and liver relative blood flow diminishes before death. The genesis of these changes as signs of a slowly developing shock is discussed. (orig.)
Abstract (German)
Die relative Durchblutung verschiedener Organe von Ratten nach Ganzkoerperbestrahlung mit Roentgenstrahlen in supraletaler Dosis wurde mit markierten 15μ-Mikrosphaeren untersucht. Sofort nach der Bestrahlung verringert sich die Gehirndurchblutung. Von der 10. bis zur 20. Stunde folgt eine Phase der verstaerkten Durchblutung zahlreicher Parenchymorgane. Ein zweites Maximum tritt von der 45. bis zur 50. Stunde und ein drittes in der 60. Stunde auf. In den meisten Organen ausser dem Herzen und der Leber nimmt die relative Durchblutung vor dem Tod ab. Die Genesis dieser Veraenderung als Anzeichen fuer einen sich langsam entwickelnden Schock wird diskutiert. (orig./AK)Additional details
Identifiers
- DOI
- 10.1007/bf01323418;
Publishing Information
- Journal Title
- Radiation and Environmental Biophysics
- Journal Volume
- 12
- Journal Issue
- 4
- Series
- Radiat. Environ. Biophys.
- Journal Page Range
- 303-313
- ISSN
- 0301-634X
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 7251369
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; BLOOD FLOW; BRAIN; CESIUM 141; CHROMIUM 51; LIVER; MICROSPHERES; RADIATION DOSE UNITS; RADIATION DOSES; RADIOBIOLOGY; RADIONUCLIDE KINETICS; RATS; RETENTION; STRONTIUM 85; SUPRALETHAL IRRADIATION; TRACER TECHNIQUES; WHOLE-BODY IRRADIATION; X RADIATION; YTTERBIUM 169
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGY; BODY; CENTRAL NERVOUS SYSTEM; CESIUM ISOTOPES; CHROMIUM ISOTOPES; DAYS LIVING RADIOISOTOPES; DIGESTIVE SYSTEM; ELECTROMAGNETIC RADIATION; ELECTRON CAPTURE RADIOISOTOPES; EVEN-ODD NUCLEI; EXTERNAL IRRADIATION; GLANDS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; IONIZING RADIATIONS; IRRADIATION; ISOMERIC TRANSITION ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; KINETICS; MAMMALS; MINUTES LIVING RADIOISOTOPES; NERVOUS SYSTEM; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; RARE EARTH NUCLEI; RODENTS; SECONDS LIVING RADIOISOTOPES; STRONTIUM ISOTOPES; UNITS; VERTEBRATES; YTTERBIUM ISOTOPES
Optional Information
- Notes
- 8 figs.; 1 tab.; 25 refs.; Updated automatically by Metadata and Full-Text Enrichment Agent