Published December 25, 1980
| Version v1
Journal article
Comparison of the cleavage of pyrimidine dimers by the bacteriophage T4 and Micrococcus luteus uv-specific endonucleases
Creators
Description
A comparison was made of the activity of the uv-specific endonucleases of bacteriophage T4 (T4 endonuclease V) and of Micrococcus luteus on ultraviolet light-irradiated DNA substrates of defined sequence. The two enzyms cleave DNA at the site of pyrimidine dimers with the same frequency. The products of the cleavage reaction are the same. The pyrimidine dimer DNA-glycosylase activity of both enzymes is more active on double-stranded DNA than it is on single-stranded DNA
Additional details
Publishing Information
- Journal Title
- J. Biol. Chem.
- Journal Volume
- 255
- Journal Issue
- 24
- Series
- J. Biol. Chem.
- Journal Page Range
- 12047-12050
- ISSN
- 0021-9258
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 13664467
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BACTERIOPHAGES; BIOCHEMISTRY; BIOLOGICAL RADIATION EFFECTS; CATALYSIS; DIMERS; DNA; ENZYMES; METABOLISM; MICROCOCCUS LUTEUS; NUCLEASES; PYRIMIDINES; ULTRAVIOLET RADIATION
- Descriptors DEC
- AZINES; BACTERIA; BIOLOGICAL EFFECTS; CHEMISTRY; ELECTROMAGNETIC RADIATION; HETEROCYCLIC COMPOUNDS; MICROCOCCUS; MICROORGANISMS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PARASITES; PHOSPHOTRANSFERASES; RADIATION EFFECTS; RADIATIONS; TRANSFERASES; VIRUSES