Published June 1978 | Version v1
Journal article Metadata-only

Influence of atropine on cystamine effects in rats

Creators

  • 1. Vojensky Lekarsky Vyzkumny a Doskolovaci Ustav J.E. Purkyne, Hradec Kralove (Czechoslovakia)

Description

The degree of protection afforded by cystamine (60 mg/kg i.p.) against radiation injuries of bone marrow of 4 - 5 weeks old rats was decreased by treatment with atropine (2 mg/kg i.p.) 20 minutes before irradiation. The exogenous spleen colonies observed on the 10th day after transplantation of tested bone marrow in preirradiated recipients served as a criterion of the efficiency of the protective combination. Vagus system activation may be important for cystamine radioprotective effects on the hemopoiesis in rats. (author)

Additional details

Additional titles

Subtitle (English)
Radioprotection of hemopoietic stem cells in vivo

Publishing Information

Journal Title
Radiobiol. Radiother.
Journal Volume
19
Journal Issue
3
Series
Radiobiol. Radiother.
Journal Page Range
361-364
ISSN
0033-8184

INIS

Country of Publication
Germany
Country of Input or Organization
German Democratic Republic
INIS RN
9404665
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
ATROPINE; BLOOD FORMATION; BONE MARROW; COBALT 60; CYSTAMINE; GAMMA RADIATION; IN VIVO; RADIATION PROTECTION; RATS; WHOLE-BODY IRRADIATION
Descriptors DEC
ALKALOIDS; AMINES; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COBALT ISOTOPES; DRUGS; ELECTROMAGNETIC RADIATION; EXTERNAL IRRADIATION; HEMATOPOIETIC SYSTEM; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IONIZING RADIATIONS; IRRADIATION; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; ORGANIC SULFUR COMPOUNDS; ORGANS; PARASYMPATHOLYTICS; RADIATIONS; RADIOISOTOPES; RADIOPROTECTIVE SUBSTANCES; RESPONSE MODIFYING FACTORS; RODENTS; TISSUES; VERTEBRATES; YEARS LIVING RADIOISOTOPES