Published March 1984
| Version v1
Journal article
Protection of microcirculation in rat brain against late radiation injury by gammaphos
- 1. Inst. of Biological Physics, Moscow, USSR
Description
The ability of a radioprotector-gammaphos to modify the development of late vascular changes in the rat brain after local irradiation with 40 and 60 Gy was investigated by means of an angiographic method. The relative number of animals with gross vascular abnormalities, the size of foci with vascular lesions, and the changes in size and number of vessels were less in the drug-treated groups. Thus, it may be possible to increase the tolerance of host tissues to curative radiation therapy by chemical radioprotectors such as gammaphos
Additional details
Publishing Information
- Journal Title
- Int. J. Radiat. Oncol., Biol. Phys.
- Journal Volume
- 10
- Journal Issue
- 3
- Series
- Int. J. Radiat. Oncol., Biol. Phys.
- Journal Page Range
- 365-368
- ISSN
- 0360-3016
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 15067254
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Numerical Data
- Descriptors DEI
- BIOMEDICAL RADIOGRAPHY; BLOOD VESSELS; BRAIN; DELAYED RADIATION EFFECTS; EXPERIMENTAL DATA; GAMMAPHOS; RADIOSENSITIVITY; RATS; X RADIATION
- Descriptors DEC
- AMINES; ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; CARDIOVASCULAR SYSTEM; CENTRAL NERVOUS SYSTEM; DATA; DIAGNOSTIC TECHNIQUES; DRUGS; ELECTROMAGNETIC RADIATION; ESTERS; INFORMATION; IONIZING RADIATIONS; MAMMALS; MEDICINE; NERVOUS SYSTEM; NUMERICAL DATA; ORGANIC COMPOUNDS; ORGANS; RADIATION EFFECTS; RADIATIONS; RADIOPROTECTIVE SUBSTANCES; RESPONSE MODIFYING FACTORS; RODENTS; THIOPHOSPHORIC ACID ESTERS; VERTEBRATES