Published January 2012 | Version v1
Journal article

Intensity-modulated radiosurgery with rapidarc for multiple brain metastases and comparison with static approach

  • 1. Department of Radiation Oncology, Moores Cancer Center, University of California, San Diego, La Jolla, CA (United States)

Description

Rotational RapidArc (RA) and static intensity-modulated radiosurgery (IMRS) have been used for brain radiosurgery. This study compares the 2 techniques from beam delivery parameters and dosimetry aspects for multiple brain metastases. Twelve patients with 2–12 brain lesions treated with IMRS were replanned using RA. For each patient, an optimal 2-arc RA plan from several trials was chosen for comparison with IMRS. Homogeneity, conformity, and gradient indexes have been calculated. The mean dose to normal brain and maximal dose to other critical organs were evaluated. It was found that monitor unit (MU) reduction by RA is more pronounced for cases with larger number of brain lesions. The MU-ratio of RA and IMRS is reduced from 104% to 39% when lesions increase from 2 to 12. The dose homogeneities are comparable in both techniques and the conformity and gradient indexes and critical organ doses are higher in RA. Treatment time is greatly reduced by RA in intracranial radiosurgery, because RA uses fewer MUs, fewer beams, and fewer couch angles.

Availability note (English)

Available from http://dx.doi.org/10.1016/j.meddos.2010.12.010

Additional details

Identifiers

DOI
10.1016/j.meddos.2010.12.010;
PII
S0958-3947(10)00207-4;

Publishing Information

Journal Title
Medical Dosimetry
Journal Volume
37
Journal Issue
1
Journal Page Range
p. 31-36
ISSN
0958-3947

INIS

Country of Publication
United States
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
44085499
Subject category
S61: RADIATION PROTECTION AND DOSIMETRY;
Descriptors DEI
BRAIN; COMPARATIVE EVALUATIONS; CRITICAL ORGANS; DOSIMETRY; METASTASES; PATIENTS; RADIATION DOSES; RADIATION MONITORS; RADIOTHERAPY; SURGERY
Descriptors DEC
BODY; CENTRAL NERVOUS SYSTEM; DOSES; EVALUATION; MEASURING INSTRUMENTS; MEDICINE; MONITORS; NERVOUS SYSTEM; NUCLEAR MEDICINE; ORGANS; RADIOLOGY; THERAPY

Optional Information

Copyright
Copyright (c) 2012 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.