Radiological–pathological correlation of negative CT biopsy results enables high negative predictive value for thoracic malignancy

Highlights: • Non-malignant thoracic biopsy results should be interpreted in the light of imaging findings. • When imaging and histological findings are concordant, conservative management is effective. • When imaging and histological findings are discordant, further sampling is warranted. To evaluate multidisciplinary team (MDT) practice of radiological–pathological correlation of non-malignant biopsy results to examine the additive effect on the predictive values of computed tomography (CT) biopsy for malignancy and their subsequent management and outcomes.