Published April 1986 | Version v1
Journal article Metadata-only

Hyperfractionated total body irradiation as part of autologous bone marrow transplantation

Creators

  • 1. Heidelberg Univ. (Germany, F.R.). Medizinische Universitaets-Poliklinik
  • 2. Heidelberg Univ. (Germany, F.R.). Zentrum Radiologie

Description

On 14 patients with acute leukemia and non-Hodgkin lymphoma autologous bone marrow transplantation (ABMT) was performed together with high dose cyclophosphamide and hyperfractionated total body irradiation. The radiotherapy was given at a total dose of 13.2 Gy distributed over eleven fractions of 1.2 Gy and four days. All eleven patients transplanted in complete remission are alive, among them ten in unmaintained complete remission at a longest observation time of two years. (orig.)

Abstract (German)

An 14 Patienten mit akuten Leukaemien und Non-Hodgkin-Lymphomen wurden autologe Knochenmarktransplantationen zusammen mit hochdosierten Cyclophosphamidgaben und hyperfraktionierter Ganzkoerperbestrahlung durchgefuehrt. Die Gesamtstrahlendosis betrug 13,2 Gy, verteilt auf 11 Fraktionen zu je 1,2 Gy und vier Tage. Von den 11 in Vollremission transplantierten Patienten haben alle ueberlebt, wobei die Vollremission bei 10 dieser Patienten nach einer Beobachtungszeit von maximal zwei Jahren nicht angehalten hatte. (orig.)

Additional details

Publishing Information

Journal Title
Strahlenther. Onkol.
Journal Volume
162
Journal Issue
4
Series
Strahlenther. Onkol.
Journal Page Range
246-247
ISSN
0179-7158

Conference

Title
Seminar and workshop on physical problems of total body irradiation.
Dates
19-20 Sep 1985.
Place
Essen (Germany, F.R.).

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
18019294
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Resource subtype / Literary indicator
Conference
Descriptors DEI
BONE MARROW CELLS; CHEMOTHERAPY; EFFICIENCY; ENDOXAN; LEUKEMIA; LYMPHOMAS; PATIENTS; RADIATION DOSES; RADIOTHERAPY; TRANSPLANTS; WHOLE-BODY IRRADIATION
Descriptors DEC
ALKYLATING AGENTS; ANIMAL CELLS; ANTIMITOTIC DRUGS; CONNECTIVE TISSUE CELLS; DISEASES; DRUGS; EXTERNAL IRRADIATION; HEMIC DISEASES; IRRADIATION; MEDICINE; NEOPLASMS; SOMATIC CELLS; THERAPY