Published February 2018
| Version v1
Journal article
Mithramycin A Enhances Tumor Sensitivity to Mitotic Catastrophe Resulting From DNA Damage
Creators
- 1. Radiation Oncology Branch, National Institutes of Health, Bethesda (United States)
- 2. Urologic Oncology Branch, National Institutes of Health, Bethesda (United States)
Description
Specificity protein 1 (SP1) is involved in the transcription of several genes implicated in tumor maintenance. We investigated the effects of mithramycin A (MTA), an inhibitor of SP1 DNA binding, on radiation response.
Availability note (English)
Available from http://dx.doi.org/10.1016/j.ijrobp.2017.09.049Additional details
Identifiers
- DOI
- 10.1016/j.ijrobp.2017.09.049;
- PII
- S0360301617339664;
Publishing Information
- Journal Title
- International Journal of Radiation Oncology, Biology and Physics
- Journal Volume
- 100
- Journal Issue
- 2
- Journal Page Range
- p. 344-352
- ISSN
- 0360-3016
- CODEN
- IOBPD3
INIS
- Country of Publication
- United States
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 54107065
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- DNA; DNA DAMAGES; GENES; NEOPLASMS; PROTEINS; SENSITIVITY
- Descriptors DEC
- DISEASES; NUCLEIC ACIDS; ORGANIC COMPOUNDS
Optional Information
- Notes
- Published by Elsevier Inc.