Renal function evaluation in hypertensive patients by 99mTc-DTPA and 99mTc-EC dynamic renography

Dynamic renography was performed in 56 cases of hypertensive patients and 29 controls using 99mTc-DTPA or 99mTc-EC. It was found that GFR of primary hypertension (PH) decreased significantly, but with no difference in the two kidneys, whereas in renovascular hypertension (RH) the GFR was lower than the PH and control group, also the GFR of diseased kidney was lower than contralateral normal side. ERPF between PH and RH was not significantly different, but both of them were lower than that of the control group. It suggested that ERPF and GFR may be some help for the understanding of renal functional state in hypertensive patients and also for evaluating the magnitude of renal injury