Published April 2010 | Version v1
Journal article Metadata-only

Influence of Magnolol on the bystander effect induced by alpha-particle irradiation

Creators

  • 1. Department of Physics and Materials Science, City University of Hong Kong, Tat Chee Avenue, Kowloon Tong (Hong Kong)
  • 2. Research and Development Division, School of Chinese Medicine, Hong Kong Baptist University, Baptist University Road, Kowloon Tong (Hong Kong)

Description

In this work, the influence of Magnolol on the bystander effect in alpha-particle irradiated Chinese hamster ovary (CHO) cells was examined. The bystander effect was studied through medium transfer experiments. Cytokinesis-block micronucleus (CBMN) assay was performed to quantify the chromosome damage induced by alpha-particle irradiation. Our results showed that the alpha-particle induced micronuclei (MN) frequencies were suppressed with the presence of Magnolol.

Availability note (English)

Available from http://dx.doi.org/10.1016/j.apradiso.2009.09.034

Additional details

Identifiers

DOI
10.1016/j.apradiso.2009.09.034;
PII
S0969-8043(09)00571-5;

Publishing Information

Journal Title
Applied Radiation and Isotopes
Journal Volume
68
Journal Issue
4-5
Journal Page Range
p. 718-721
ISSN
0969-8043
CODEN
ARISEF

Conference

Title
7. international topical meeting on industrial radiation and radio isotope measurement application
Acronym
IRRMA-7
Dates
22-27 Jun 2008
Place
Prague (Czech Republic)

INIS

Country of Publication
United Kingdom
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
41068551
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
ALPHA PARTICLES; BIOLOGICAL RADIATION EFFECTS; CHO CELLS; CHROMOSOMES; DAMAGE; HAMSTERS; IRRADIATION; OVARIES
Descriptors DEC
ANIMAL CELLS; ANIMALS; BIOLOGICAL EFFECTS; BODY; CHARGED PARTICLES; FEMALE GENITALS; GONADS; IONIZING RADIATIONS; MAMMALS; ORGANS; RADIATION EFFECTS; RADIATIONS; RODENTS; SOMATIC CELLS; VERTEBRATES

Optional Information

Copyright
Copyright (c) 2009 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.