Published 1978 | Version v1
Miscellaneous Metadata-only

The role of DNA injury and repair in radiation aging and carcinogenesis

Creators

Description

The role of DNA repair in the processes of radiation injury, senescence and carcinogenesis is discussed. The data which favour a decisive role of DNA impairment and repair processes in the radiation-induced senescence and carcinogenesis are subjected to analysis. Accumulation of DNA impairments are shown to be the mechanism limiting the life-span. Increment in the ''safety factor'' of the DNA repair system appears to be one of the effective preventive means of aging induced by ionizing radiation

Additional details

Additional titles

Original title (Russian)
Роль повреждения и репарации ДНК в радиационном старении и канцерогенезе

Publishing Information

Imprint Title
Information report. No. 21
Journal Page Range
p. 38-43.
Report number
INIS-mf--5636

Conference

Title
Plenum of the scientific council of the Academy of Sciences of the USSR on radiobiology problems devoted to the DNA reparation in mammal cells.
Dates
Mar 1977.
Place
Pushchino, USSR.

INIS

Country of Publication
USSR
Country of Input or Organization
USSR
INIS RN
12575333
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
BIOLOGICAL REPAIR; CARCINOGENESIS; DELAYED RADIATION EFFECTS; DNA; GENETIC RADIATION EFFECTS; IONIZING RADIATIONS; LIFE SPAN
Descriptors DEC
BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BIOLOGICAL RECOVERY; GENETIC EFFECTS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; PATHOGENESIS; RADIATION EFFECTS; RADIATIONS

Optional Information

Notes
Imprint:Informatsionnyj bulleten'. Vypusk 21.