Published October 1981 | Version v1
Journal article Metadata-only

A non-invasive method for measurement of glomerular filtration without immobilisation of the patient

Creators

  • 1. Erlangen-Nuernberg Univ., Erlangen (Germany, F.R.). Inst. und Poliklinik fuer Nuklearmedizin

Description

The report concerns a new technique for measurement of glomerular filtration rate (GFR) by use of a CdTe-semiconductor system with a portable solid state memory for data storage. The time activity curves are measured at both sides of the sternum infraclavicularly, data analysis is performed using a monocompartment model. The results in one patient's investigation by use of two detectors and two plasma samples do not vary significantly providing indirect evidance for good reproducibility of the technique. The correlation between sup(99m)Tc-DTPA-clearance and endogenous creatinineclearance is satisfactory. This new technique is very useful for clinical routine work because of low costs and no need of skilled technician's time. (orig.)

Abstract (German)

Es wird ueber eine neue Moeglichkeit der Messung des Glomerulumfiltrats berichtet unter Verwendung eines CdTe-Halbleitersystems mit portablem Festspeicher zur Registrierung einer Zeitaktivitaetskurve ueber der oberen Thoraxapertur. Die Auswertung nach einem Einkammermodell unter Verwendung von sup(99m)Tc-DTPA ergibt stabile Clearancewerte, die kaum abhaengig sind von Detektorposition und Zeitpunkt der Blutabnahme. Die Korrelation mit der endogenen Kreatininclearance ist befriedigend. Die breite Einfuehrung dieser wenig kostenintensiven und wenig personalintensiven Methode ist erstrebenswert. (orig.)

Additional details

Additional titles

Original title (German)
Eine nicht-invasive Methode zur Messung der glomerulaeren Filtration ohne Immobilisierung des Patienten

Publishing Information

Journal Title
Nuc Compact
Journal Volume
12
Journal Issue
5
Series
Nuc Compact.
Journal Page Range
216-219
ISSN
0344-3752

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
13671924
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
ACCURACY; ANALOG SYSTEMS; BLOOD SERUM; DIAGNOSIS; DTPA; GAMMA DETECTION; GLOMERULI; ISOMERIC NUCLEI; MEASURING METHODS; PATIENTS; RADIOPHARMACEUTICALS; RENAL CLEARANCE; TECHNETIUM 99
Descriptors DEC
AMINO ACIDS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARBOXYLIC ACIDS; CHELATING AGENTS; CLEARANCE; DRUGS; EXCRETION; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; KIDNEYS; LABELLED COMPOUNDS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; RADIATION DETECTION; RADIOACTIVE MATERIALS; RADIOISOTOPES; TECHNETIUM ISOTOPES; YEARS LIVING RADIOISOTOPES