Comparative impurity levels in iodine-123 produced by (p,2n) and (p,5n) reactions
Description
Samples of two commercially available diagnostic drug products, one containing 123I produced by the 124Te(p,2n) → 123I reaction and the other containing 123I produced by the 127I(p,5n)123Xe → 123I reaction, were analyzed by gamma-ray spectroscopy. The impurities 124I, 125I, 126I, and 121Te were found in the (p,2n)-produced 123I, whereas only 125I and 121Te were detected in the (p,5n)-produced 123I. Quantitatively, the level of impurities measured in (p,2n)-produced 123I was substantially higher (4.0%) than that found in the (p,5n)-produced 123I (1.0%). Also, the gamma emissions from the impurities in the (p,2n)-produced 123I were primarily high-energy photons (i.e., above 159 KeV), which adversely affect both patient radiation dose and image quality
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Additional details
Publishing Information
- Imprint Title
- Developing role of short-lived radionuclides in nuclear medical practice. DOE symposium series: 56
- Journal Page Range
- p. 471-474.
- Report number
- CONF-820523--
Conference
- Title
- International symposium on the developing role of short-lived radionuclides in nuclear medical practice.
- Dates
- 3-5 May 1982.
- Place
- Washington, DC (USA).
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 17019427
- Subject category
- S07: ISOTOPES AND RADIATION SOURCES;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- GAMMA SPECTROSCOPY; IMAGES; IMPURITIES; IODINE 123; IODINE 124; IODINE 125; IODINE 126; ISOTOPE PRODUCTION; PROTON REACTIONS; RADIATION DOSES; RADIOISOTOPE GENERATORS; RADIOPHARMACEUTICALS; TELLURIUM 121
- Descriptors DEC
- BARYON REACTIONS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; DAYS LIVING RADIOISOTOPES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; EVEN-ODD NUCLEI; HADRON REACTIONS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IODINE ISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MATERIALS; NUCLEAR REACTIONS; NUCLEI; NUCLEON REACTIONS; ODD-EVEN NUCLEI; ODD-ODD NUCLEI; RADIOACTIVE MATERIALS; RADIOISOTOPES; SPECTROSCOPY; TELLURIUM ISOTOPES