Published February 2016 | Version v1
Miscellaneous Restricted

Alternative(s) to perfusion scintigraphy in case of suspected non-massive pulmonary embolism in pregnant women in the event of a complete shortage of technetium-99m

Description

Due to several periods of worldwide supply shortage of technetium-99m (Tc-99m), a radioactive element needed to perform lung perfusion scintigraphy in case of suspected non-massive pulmonary embolism (PE), the Ministry of Health (DGS) asked HAS to determine if, in the event of complete shortage of this isotope, one (or more) test(s) could replace it without risk to the pregnant woman. Currently, Tc-99m lung perfusion scintigraphy is the medical imaging test of choice in pregnant women initially without signs of shock or hypotension (especially if the triage chest x-ray is normal) when this test is readily accessible for the clinician. Offering good diagnostic performances, lung perfusion scintigraphy is not very radiating for the mother and foetus. The objective of this assessment was not to question the current standard strategy in this situation or to establish good practice guidelines

Abstract (French)

En raison de plusieurs episodes de penurie mondiale d'approvisionnement en technetium 99m (Tc99m), radioelement necessaire a la realisation de la scintigraphie pulmonaire de perfusion en cas de suspicion d'embolie pulmonaire (EP) non massive, la Direction generale de la sante (DGS) a demande a la HAS de determiner si, en situation de penurie complete pour cet isotope, un (ou plusieurs) examen(s) pourrai(en)t se substituer a elle sans perte de chance chez la femme enceinte. Actuellement, la scintigraphie pulmonaire de perfusion au Tc99m est une imagerie medicale de choix chez la femme enceinte initialement sans signe de choc ou d'hypotension (notamment si la radiographie de thorax de triage est normale) lorsque cet examen est rapidement accessible pour le clinicien. Presentant de bonnes performances diagnostiques, la scintigraphie pulmonaire de perfusion est peu irradiante pour le couple mere-foetus. L'objectif de cette evaluation n'etait pas de remettre en cause la strategie actuelle de reference dans cette situation ni d'etablir des recommandations de bonne pratique

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Additional details

Additional titles

Original title (French)
Alternative(s) a la scintigraphie de perfusion en cas de suspicion d'embolie pulmonaire non massive chez la femme enceinte dans l'hypothese d'une penurie complete en technetium-99m. Rapport d'evaluation technologique - Fevrier 2016

Publishing Information

ISBN
978-2-11-139136-9
Imprint Pagination
61 p.
Report number
INIS-FR--22-0308

Optional Information

Notes
32 refs.; Available from the INIS Liaison Officer for France, see the INIS website for current contact and E-mail addresses