Published May 1972 | Version v1
Miscellaneous Open

Harmonic analysis of the spontaneous electrical activity in the rabbit brain during hypoxia

Creators

Description

An objective method was developed to analyse the evolution of EEG signals during hypoxia. Following a review of the literature on the techniques and results reported, digital analysis was chosen. A detailed description of the experimental procedure is given: electrode implantation, functional monitoring (arterial pO2 and pCO2...), data acquisition and processing. The analysis of the electrical activity of the rabbit dorsal hippocampus following inhalation of various gas mixtures poor in oxygen (10, 7, 5, 3, 0 per cent) is given as an example. The analysis of the frequencies on several bands between 0 and 40 Hz is completed by an energetic study. The advantages and drawbacks of the method are shown, which allows a comparison with other investigations about the same processes. The physiopathological problems raised by anoxia are discussed and the further developments of the methods are shown. (authors)

Abstract (French)

Une methode objective pour analyser l'evolution du signal EEG au cours de l'hypoxie est decrite. Apres l'etude bibliographique des techniques et des resultats anterieurs, le choix est porte sur l'analyse digitale dont on expose les principes qui autorisent son application a l'electroencephalographie. Le protocole experimental est defini avec precision: implantation des animaux, controles fonctionnels (pO2 et pCO2 arterielle...), acquisition et exploitation des donnees. A titre d'exemple est rapportee l'analyse de l'activite electrique de l'hippocampe dorsal du lapin soumis a l'inhalation de divers melanges appauvris en oxygene (10, 7, 5, 3, 0 pour cent). Une etude energetique complete l'analyse des frequences realisee sur plusieurs bandes entre 0 et 40 Hz. Les avantages et inconvenients du procede sont soulignes et permettent la comparaison avec d'autres travaux traitant des memes phenomenes. La discussion souleve les problemes physiopathologiques de l'anoxie et montre les extensions possibles de la methode. (auteurs)

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Additional details

Additional titles

Original title (French)
Analyse harmonique de l'activite electrique cerebrale spontanee du lapin au cours de l'hypoxie

Publishing Information

Imprint Pagination
106 p.
Report number
CEA-R--4277

INIS

Country of Publication
France
Country of Input or Organization
France
INIS RN
54027887
Subject category
S60: APPLIED LIFE SCIENCES;
Descriptors DEI
ANOXIA; BIOLOGICAL RECOVERY; CORRELATION FUNCTIONS; DATA ACQUISITION SYSTEMS; DIGITAL FREQUENCY ANALYSIS; ELECTRODES; ELECTROENCEPHALOGRAPHY; ERGODIC HYPOTHESIS; FOURIER TRANSFORMATION; HARMONICS; HIPPOCAMPUS; INHALATION; ISCHEMIA; NUMERICAL ANALYSIS; POWER DENSITY; RABBITS
Descriptors DEC
ANEMIAS; ANIMALS; BODY; BRAIN; CARDIOVASCULAR DISEASES; CENTRAL NERVOUS SYSTEM; DIAGNOSTIC TECHNIQUES; DISEASES; FREQUENCY ANALYSIS; FUNCTIONS; HEMIC DISEASES; HYPOTHESIS; INTAKE; INTEGRAL TRANSFORMATIONS; MAMMALS; MATHEMATICS; NERVOUS SYSTEM; ORGANS; OSCILLATIONS; SYMPTOMS; TRANSFORMATIONS; VASCULAR DISEASES; VERTEBRATES

Optional Information

Notes
88 refs.; Available from the INIS Liaison Officer for France, see the INIS website for current contact and E-mail addresses