Published 1990 | Version v1
Report Metadata-only

Synthesis and evaluation of radioiodinated tetrafluorophenyl m-iodobenzoate and tetrafluorophenyl-5-iodopentenoates as conjugating agents for proteins and antibodies

Creators

  • 1. Northeastern Univ., Boston, MA (United States)
  • 2. Massachusetts General Hospital, Boston (United States)

Description

A new synthesis of the radioconjugating agent tetrafluorophenyl-m-iodobenzoate has been developed, and new derivatives of tetrafluorophenyl-5-iodopentenoate have been synthesized. These compounds, labelled with radioactive iodine, have been conjugated to antibodies, and the tissue distribution determined

Additional details

Publishing Information

Imprint Title
Eighth international symposium on radiopharmaceutical chemistry. Abstracts: Final report
Imprint Pagination
458 p.
Journal Page Range
p. 229-230.
Report number
DOE/ER/60968--1

Conference

Title
8. international symposium on radiopharmaceutical chemistry.
Dates
24-29 Jun 1990.
Place
Princeton, NJ (United States).

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
23029794
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY; S62: RADIOLOGY AND NUCLEAR MEDICINE;
Resource subtype / Literary indicator
Conference, Non-conventional Literature
Descriptors DEI
ANTIBODIES; CHEMICAL PREPARATION; ESTERS; EVALUATION; FLUORINATED AROMATIC HYDROCARB; IODINE 125; LABELLED COMPOUNDS; LABELLING; MOLECULAR STRUCTURE; RADIOIMMUNODETECTION; TIN COMPLEXES
Descriptors DEC
AROMATICS; BETA DECAY RADIOISOTOPES; COMPLEXES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; ELECTRON CAPTURE RADIOISOTOPES; HALOGENATED AROMATIC HYDROCARB; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IODINE ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC FLUORINE COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; RADIOASSAY; RADIOISOTOPES; SYNTHESIS; TRACER TECHNIQUES

Optional Information

Contract/Grant/Project number
Contract FG02-86ER60460
Secondary number(s)
CONF-9006363--Absts.