A scintiscan study using leukocytes
Description
A method of labelling leukocytes with 111-In-oxine is described that is easy to handle, reproducible and requires no sophisticated hardware. It is based on a leukocyte concentrate prepared from whole blood, which has an average cell content of 64.8%. Seventy-two patients selected from among those undergoing nephrologico-urological and neurological procedures or accident surgery were subjected to preliminary wholebody scintiscanning as well as a scintiscan study using leukocytes. It was calculated that the method is able to reveal the presence of an abscess with a sensitivity of 77%, a specificity of 98% and an accuracy of 89%. This examination may prove equally useful to follow up a confirmed inflammation, to determine its exact type and extent and to make a clear diagnostic distinction between an inflammatory process and a tumour. (TRV)
Availability note (English)
Available from the library of Medizinische Hochschule Hannover (Germany, F.R.).Abstract (German)
Eine praktikable, reproduzierbare und geraetetechnisch wenig aufwendige Methode der Leukozytenmarkierung mit 111 In-Oxin, ausgehend von einem Leukozyten-Konzentrat aus Vollblut mit im Mittel 64.8% Zellen im Konzentrat, wird vorgestellt. 72 Patienten aus dem nephrologisch-urologischen, neurologischen und unfallchirurgischen Bereich wurden einer orientierenden Ganzkoerper- und der Leukozytenszintigraphie unterzogen. In dieser Abszess-Diagnostik ergab sich fuer die Methode eine Sensitivitaet von 77%, eine Spezifitaet von 98% und eine Genauigkeit von 89%. Ausmass, Charakterisierung und Verlaufskontrolle einer bekannten Entzuendung und Differentialdiagnose gegenueber einem Tumor sind neben dem Abszessnachweis weitere Indikationen fuer die Untersuchung. (TRV)Additional details
Additional titles
- Subtitle (English)
- Preparation and 111-In-oxine labelling of leukocytes and their clinical uses
- Original title (German)
- Die Leukozytenszintigraphie
- Original subtitle (German)
- Praeparation und Markierung von Leukozyten mit 111-Indium-Oxin und ihre klinische Anwendung.
Publishing Information
- Imprint Pagination
- 140 p.
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 20056700
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Thesis, Non-conventional Literature
- Descriptors DEI
- ABSCESSES; ACCURACY; DIAGNOSIS; INDIUM 111; LABELLING; LEUKOCYTES; OXINE; PATIENTS; SCINTISCANNING
- Descriptors DEC
- AZINES; BETA DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DISEASES; ELECTRON CAPTURE RADIOISOTOPES; HETEROCYCLIC COMPOUNDS; HYDROXY COMPOUNDS; INDIUM ISOTOPES; INFLAMMATION; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MATERIALS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PATHOLOGICAL CHANGES; PYRIDINES; QUINOLINES; RADIOISOTOPE SCANNING; RADIOISOTOPES