Dynamics of the immune system state in the residents of Kiev after the Chernobyl accident

After the Chernobyl accident, decrease in cytotoxic activity of natural cytotoxic cells (NCC) and antibody-dependent cytotoxic cells (ABDCC) of the peripheral blood, disturbance of regulatory T-lymphocytes subpopulations balance, increase of the amount of lymphoid immature cells in blood serum, increase of M, G, and A immunoglobulins levels, decrease of the amount of saliva secretory A immunoglobulin were revealed. The most prominent changes of reactivity were observed during the first two years after the accident, the values (except for NCC) became normal by 1990. In vitro experiments revealed the possibility to stimulate NCC functional activity with immunomodulators having different action