Published May 1995 | Version v1
Journal article Metadata-only

The preparation and biological evaluation of a potential tumor therapeutic 103,109Pd radiocolloid

Creators

  • 1. Southwest Inst. of Nuclear Physics and Chemistry, Chengdu (China)
  • 2. General Hospital of Kunming Military Region (China)

Description

The 103,109Pd radiocolloid is obtained after treating irradiated metallic palladium powder in reactor with nitric acid and hydrochloric acid in the presence of ascorbic acid (reducing agent) as well as glucose and gelatin (protective agent). The size of Pd radiocolloid particles is in the range of 150-400 nm. Animal tests indicated that the 103,109Pd radiocolloid is injected into a rat in a dose as much as 100 times of that for a patient (1.2 GBq/50 kg)

Additional details

Publishing Information

Journal Title
Journal of Isotopes
Journal Volume
8
Journal Issue
2
Journal Page Range
p. 65-70.
ISSN
1000-7512

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
27018698
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY; S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
ASCORBIC ACID; COLLOIDS; GELATIN; GLUCOSE; HYDROCHLORIC ACID; IMAGES; INJECTION; NEOPLASMS; NEUTRON REACTIONS; NITRIC ACID; PALLADIUM; PALLADIUM 103; PALLADIUM 109; PATIENTS; RADIOPHARMACEUTICALS; RATS; SAMPLE PREPARATION
Descriptors DEC
ALDEHYDES; ANIMALS; BARYON REACTIONS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CARBOHYDRATES; CHLORINE COMPOUNDS; DAYS LIVING RADIOISOTOPES; DISEASES; DISPERSIONS; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; ELEMENTS; EVEN-ODD NUCLEI; HADRON REACTIONS; HALOGEN COMPOUNDS; HEXOSES; HOURS LIVING RADIOISOTOPES; HYDROGEN COMPOUNDS; INORGANIC ACIDS; INORGANIC COMPOUNDS; INTAKE; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MAMMALS; MAN; MATERIALS; METALS; MINUTES LIVING RADIOISOTOPES; MONOSACCHARIDES; NITROGEN COMPOUNDS; NUCLEAR REACTIONS; NUCLEI; NUCLEON REACTIONS; ORGANIC COMPOUNDS; OXYGEN COMPOUNDS; PALLADIUM ISOTOPES; PLATINUM METALS; PRIMATES; PROTEINS; RADIOACTIVE MATERIALS; RADIOISOTOPES; RODENTS; SACCHARIDES; TRANSITION ELEMENTS; VERTEBRATES; VITAMINS