Published January 2019 | Version v1
Journal article

A new MRI marker of ataxia with oculomotor apraxia

  • 1. Université de Lyon, Lyon 1 University, Lyon, F-69373 (France)
  • 2. Hospices Civils de Lyon, Neurology D and Neuro-Ophthalmology Unit, Hôpital Neurologique Pierre Wertheimer, Bron, F-69677 (France)
  • 3. Nehme and Therese Tohme Multiple Sclerosis Center, Faculty of Medicine, American University of Beirut, Beirut, 1107 2020 (Lebanon)
  • 4. CREATIS, INSERM U1206 & CNRS UMR 5220, Lyon, F-69000 (France)
  • 5. Centre de Neurosciences Cognitives de Lyon, CNRS UMR 5229, Bron F-69500 (France)
  • 6. Hospices Civils de Lyon, Neurology C, Hôpital Neurologique Pierre Wertheimer, Bron, F-69677 (France)
  • 7. Hospices Civils de Lyon, Explorations Fonctionnelles Neurologiques, Hôpital de la Croix Rousse, Lyon, F-69004 (France)
  • 8. Lyon Neuroscience Research Center, INSERM U1028 CNRS UMR5292, Team ImpAct, Bron, F-69676 (France)
  • 9. Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Service de Radiologie and Laboratoire d'Anatomie de Rockefeller, Lyon, F-69000 (France)

Description

Highlights: • The hypointense iron-induced SWI signal of the DN is not observed in AOA patients. • The absence of the DN hypointense signal is a new sign of outstanding specific value. • DN signal on FLAIR and SWI could be considered as a diagnostic criterion of AOA. - Abstract: Purpose: Evaluate the specificity and sensitivity of disappearance of susceptibility weighted imaging (SWI) dentate nuclei (DN) hypointensity in oculomotor apraxia patients (AOA).

Availability note (English)

Available from http://dx.doi.org/10.1016/j.ejrad.2018.11.035

Additional details

Identifiers

DOI
10.1016/j.ejrad.2018.11.035;
PII
S0720048X18304303;

Publishing Information

Journal Title
European Journal of Radiology
Journal Volume
110
Journal Page Range
p. 187-192
ISSN
0720-048X
CODEN
EJRADR

INIS

Country of Publication
Netherlands
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
51013655
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
GENETICS; IRON; NMR IMAGING; NUCLEI; PATIENTS; SENSITIVITY; SIGNALS; SPECIFICITY
Descriptors DEC
BIOLOGY; DIAGNOSTIC TECHNIQUES; ELEMENTS; METALS; TRANSITION ELEMENTS

Optional Information

Notes
© 2018 The Authors. Published by Elsevier B.V.